Relationship Graph Explorer

Follow the connections

Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.

🌿

Herb

→

→

→

→

🧪

Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

15 Diseases matching "rheumatoid arthritis"

Rheumatoid Arthritis Rheumatoid Arthritis of Ankle Rheumatoid arthritis, unspecified Rheumatoid Arthritis In Remission Rheumatoid Arthritis, Systemic Juvenile Juvenile Arthritis Rheumatoid Lung Disease Early Rheumatoid Arthritis Juvenile Rheumatoid Arthritis Juvenile Chronic Polyarthritis Seropositive Rheumatoid Arthritis Seronegative Rheumatoid Arthritis Progression of Rheumatoid Arthritis Pauciarticular Juvenile Rheumatoid Arthritis Polyarticular Juvenile Idiopathic Arthritis, Rheum

🏥 Disease / Health Topic

Rheumatoid Arthritis

Open on HERB 2.0 ↗

Clinical Trials

Meta-Analyses

PubMed References

📋 Sample Trials

NCT03131973

Effects of Concomitant Administration of BMS-986195 on Methotrexate, Caffeine, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin

Completed · Phase 1

NCT03131973

Effects of Concomitant Administration of BMS-986195 on Methotrexate, Caffeine, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin

Completed · Phase 1

NCT04911127

Therapeutic Response of Cannabidiol in Rheumatoid Arthritis

Completed · Phase 1

📊 Sample Meta-Analyses

CRD42018105272

The incidence of adverse events of andrographis paniculata: a systematic review and meta-analysis

- Diagnoses of upper respiratory tract infections include common cold, laryngiti

CRD42020172406

Potential effects of pomegranate (Punica granatum) on rheumatoid arthritis: A systematic review

Rheumatoid arthritis

CRD42019133047

A systematic review of the potential effects of Nigella sativa on rheumatoid arthritis

Rheumatoid arthritis

📚 Sample References

None linked yet.

🏥 All Disease / Health Topic data fields for Rheumatoid Arthritis

🏥 Names

Disease Name

Rheumatoid Arthritis

Alias Names

Arthritis, Rheumatoid; Rheumatoid Arthritis; Rheumatoid Arthritis, Unspecified

Topic Type

syndrome

🧬 Ontology Classifications

DisGeNET Type

disease

UMLS Type

Disease or Syndrome

MeSH Class

Skin and Connective Tissue Diseases; Immune System Diseases; Musculoskeletal Diseases

HPO Class

Abnormality of the skeletal system

DO Class

disease of anatomical entity

🔗 External References

HERB DB

MeSH

ICD-10

OMIM

HPO

Disease Ontology

7148

DisGeNET

C0003873

🔍 Raw view — every non-empty column on this row (32 fields)

name

Rheumatoid Arthritis

alias name

Arthritis, Rheumatoid; Rheumatoid Arthritis; Rheumatoid Arthritis, Unspecified

topic type

syndrome

disgenet disease type

disease

umls disease type

Disease or Syndrome

mesh disease class

Skin and Connective Tissue Diseases; Immune System Diseases; Musculoskeletal Diseases

hpo disease class

Abnormality of the skeletal system

do disease class

disease of anatomical entity

umls disease type id

T047

mesh disease class id

C05; C17; C20

hpo disease class id

HP:0000924

do disease class id

DOID:7

herb disease id

HBDIS000248

disgenet id

C0003873

mesh id

D001172

hpo id

HP:0001370

do id

7148

icd10 id

M06.9

omim id

180300

tcmsp disease id

702

🌿 Related Herbs

1 · contains this compound

Ephedra

Ma Huang

⚗️ Related Ingredients

4 · compounds in this herb

🧬 Gene / Protein Targets

1 · genes implicated in this disease

Transcription factor AP-1

📋 Clinical Trials

12 · subject of clinical study

NCT03131973 Effects of Concomitant Administration of BMS-986195 on Methotrexate, Caffeine, M

→ Rheumatoid Arthritis

NCT03131973 Effects of Concomitant Administration of BMS-986195 on Methotrexate, Caffeine, M

→ Rheumatoid Arthritis

NCT04911127 Therapeutic Response of Cannabidiol in Rheumatoid Arthritis

→ Rheumatoid Arthritis|Cannabis

NCT01311622 Effects of Administration of Fostamatinib on Blood Concentrations of Warfarin in

→ Rheumatoid Arthritis|Healthy Subjects

NCT01355354 Effects of Administration of Fostamatinib on Blood Concentrations of Digoxin in

→ Healthy Volunteers|Rheumatoid Arthritis

NCT02254655 The Effect of Puerarin Injection on Carotid Intima-Media Thickness in Patients W

→ Rheumatoid Arthritis

NCT00399282 Omega-3 and Vitamin E Supplementation in Patients With Rheumatoid Arthritis

→ Rheumatoid Arthritis

NCT02456844 Study to Investigate the Effect of BMS-986142 on the Pharmacokinetics (PK) of Me

→ Rheumatoid Arthritis

NCT00221000 Safety and Efficacy of Extracorporeal Photoimmune Therapy With UVADEX for the Tr

→ Rheumatoid Arthritis

NCT01582880 Use of Cross-linked Donor Corneas as Carriers for the Boston Keratoprosthesis

→ Chemical Injuries|Unspecified Complication of Corn

NCT05443360 To Evaluate the Efficacy and Safety of Amorphous Calcium Carbonate in RA Patient

→ Rheumatoid Arthritis|Osteopenia or Osteoporosis

NCT05443360 To Evaluate the Efficacy and Safety of Amorphous Calcium Carbonate in RA Patient

→ Rheumatoid Arthritis|Osteopenia or Osteoporosis

📊 Meta-Analyses

12 · systematic review

CRD42018105272 The incidence of adverse events of andrographis paniculata: a systematic review

→ - Diagnoses of upper respiratory tract infections

CRD42020172406 Potential effects of pomegranate (Punica granatum) on rheumatoid arthritis: A sy

→ Rheumatoid arthritis

CRD42019133047 A systematic review of the potential effects of Nigella sativa on rheumatoid art

→ Rheumatoid arthritis

CRD42019128607 Utility of coronary calcium scoring in connective tissue disorders for the evalu

→ Connective tissue diseases: 1. Rheumatoid arthriti

CRD42020197182 Coronary Calcium Score as Predictor of Subclinical Atherosclerosis in Autoimmune

→ Diseases such as systemic lupus erythematosus, rhe

CRD42018086769 Effectiveness of alpha-lipoic acid supplementation for rheumatoid arthritis pati

→ Alpha-lipoic acid supplementation Alpha-lipoic ac

CRD42020176979 Effect of caffeine consumption on efficacy and tolerance of methotrexate in rheu

→ This study is focused on the use of methotrexate i

CRD42021227665 Type of Coffee, Tea, Caffeine intake and Risk of Rheumatoid Arthritis: A Dose–Re

→ Rheumatoid arthritis (RA) is a most prevalent auto

CRD42018087201 Effectiveness of curcumin and turmeric extract for rheumatoid arthritis patients

→ Curcumin and turmeric extract for rheumatoid arthr

CRD42020168341 Efficacy and Safety of Curcumin in Rheumatoid Arthritis: a Systematic Review and

→ Rheumatoid Arthritis (RA)

CRD42020187868 Curcumin and rheumatoid arthritis: A systematic review of literature

→ Rheumatoid arthritis (RA) is a chronic systemic in

CRD42022361992 Effect of curcumin on rheumatoid arthritis: a systematic review and meta-analysi

→ The main areas of research are rheumatoid arthriti

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: ACTIVE — direct link via herb_ingredients
Ingredient ↔ Target: ACTIVE — direct link via ingredient_targets
Target ↔ Disease: ACTIVE — direct link via target_health_topics
Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables