Relationship Graph Explorer

Follow the connections

Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.

🌿

Herb

→

→

→

→

🧪

Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases

Quick picks: Da Ma Green Tea Common Olive Peanut Ginkgo Leaf; Ginkgo Folium Pomegranate Fruit Sucrose Cocoa Linseed Honey

🌿 Herb

Ephedra

Open on HERB 2.0 ↗

Clinical Trials

Meta-Analyses

PubMed References

Top Conditions Studied with Ephedra

Overweight and obesity. 1 Clinical research in traditional Chinese medicine 1 Primary nephrotic syndrome (PNS) is a prevalent glomerular d 1

📋 Sample Trials

None linked yet.

📊 Sample Meta-Analyses

CRD42022325892

Meta-analysis of ephedra appendage fine spice decoction for the treatment of allergic rhinitis

Clinical research in traditional Chinese medicine

CRD42023387895

Efficacy and Safety of Ephedra for Treating Overweight & Obesity : A Systematic Review, Meta-Analysis, and Exploratory Study for Dose-Response

Overweight and obesity.

CRD42023403255

Ephedra-containing traditional Chinese medicine for Primary Nephrotic Syndrome in Adults: A systematic review and meta-analysis

Primary nephrotic syndrome (PNS) is a prevalent glomerular disease characterised

📚 Sample References

PMID 27376063

Efficient Use of a Crude Drug/Herb Library Reveals Ephedra Herb As a Specific Antagonist for TH2-Specific Chemokine Receptors CCR3, CCR4, and CCR8

Front Cell Dev Biol · 2016

PMID 35684137

Antioxidant and Antihyperglycemic Effects of Ephedra foeminea Aqueous Extract in Streptozotocin-Induced Diabetic Rats

Nutrients · 2022

🌿 All Herb data fields for Ephedra

🌿 Names

Pinyin Name

Ma Huang

中文名 (Chinese)

麻黄

Latin Name

Ephedrae Herba; Herba Ephedrae

English Name

Ephedra

Alias Names

龙沙; 狗骨; 卑相; 卑盐

☯ TCM Properties

Properties (性味)

Pungent; Slightly Bitter; Warm

Meridians (归经)

Lung; Bladder

Part Used

Herbaceous twigs

Therapeutic Class (EN)

Pungent-Warm Exterior-Releasing Medicinal

功效分类 (CN)

辛温解表药

🩺 Clinical Profile

Function (功能)

To induce perspiration for dispelling cold, to relieve asthma, and to cause diuresis.

Indication (主治)

Wind-cold exterior repletion syndrome, headache without sweating, headache and generalized pain, cough, fever, fever and aversion to wind, absence of sweating, congesting lung, non-diffusion of lung qi, cough and asthma, bronchial asthma, wind water edema, nasal congestion, allergic rhinitis, inhibited urination, wind-damp impediment pain, muscle numbness, wind papule itching, yin flat abscess and phlegm node.

Clinical Manifestations

1. its effects on cardiovascular system are similar to epinephrine in many aspects, but persist seven to ten times longer. the myocardial contractility and cardiac output are augmented and cardiac, cerebral and muscular blood flows are increased.2. its br

🔗 External References

HERB DB

HERB003658 ↗

SymMap

264 ↗

TCMID

1660

TCMSP

264

TCM-ID

1398

🔍 Raw view — every non-empty column on this row (31 fields)

name

Ephedra

chinese name

麻黄

pinyin name

Ma Huang

latin name

Ephedrae Herba; Herba Ephedrae

english name

Ephedra

properties english

Pungent; Slightly Bitter; Warm

meridians english

Lung; Bladder

use part

Herbaceous twigs

symmap herb id

264

tcmid id

1660

tcmsp id

264

herb id str

HERB003658

function text

To induce perspiration for dispelling cold, to relieve asthma, and to cause diuresis.

indication

clinical manifestations

therapeutic en class

Pungent-Warm Exterior-Releasing Medicinal

therapeutic cn class

辛温解表药

tcm id id

1398

alias name

龙沙; 狗骨; 卑相; 卑盐

⚗️ Related Ingredients

29 · compounds in this herb

4-(2-docosyloxycarbonyl-vinyl)-benzoic,acid

PubChem CID 101237996

4-(2-eicosyloxycarbonyl-vinyl)-benzoic,acid

PubChem CID 101237995

Beta-sitosterol

PubChem CID 222284

Campest-5-en-3beta-ol

PubChem CID 171336773

Mahuannin j

PubChem CID 171336776

24-Ethylcholest-4-en-3-one

poriferast-5-en-3beta-ol

🧬 Gene / Protein Targets

30 · gene targets via constituent compounds

KCNH2

Gene KCNH2

PGR

Gene PGR

NCOA2

Gene NCOA2

Prostaglandin G/H synthase 1

Prostaglandin G/H synthase 2

Heat shock protein HSP 90

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, gamma isoform

Gamma-aminobutyric-acid receptor alpha-2 subunit

Muscarinic acetylcholine receptor M2

Gamma-aminobutyric acid receptor subunit alpha-1

mRNA of PKA Catalytic Subunit C-alpha

Muscarinic acetylcholine receptor M1

Alpha-1B adrenergic receptor

Apoptosis regulator Bcl-2

Apoptosis regulator BAX

Transcription factor AP-1

Caspase-3

Sodium channel protein type 5 subunit alpha

Beta-2 adrenergic receptor

Caspase-9

Caspase-8

Protein kinase C alpha type

Transforming growth factor beta-1

Serum paraoxonase/arylesterase 1

Dopamine D1 receptor

Muscarinic acetylcholine receptor M3

Muscarinic acetylcholine receptor M4

CGMP-inhibited 3',5'-cyclic phosphodiesterase A

5-hydroxytryptamine 2A receptor

Gamma-aminobutyric-acid receptor alpha-5 subunit

📜 Related Formulas

20 · contains this herb

E Li Hong Ke Chuan Oral Liquid

E Li Hong Ke Chuan Kou Fu Ye

An Sou Syrup

An Sou Tang Jiang

Bai Ke Jing Syrup; Baikejing Syrup

Bai Ke Jing Tang Jiang

Bai Hua Ding Chuan Tablet

Bai Hua Ding Chuan Pian

Bai Hua Ding Chuan Pill

Bai Hua Ding Chuan Wan

Ban Xia Zhi Ke Tang Jiang

Baokening Granule; Bao Ke Ning Granule

Bai Zhi Shan Gan Mao Granule

Bai Zhi Shan Gan Mao Ke Li

Bao Yuan Pill

Bao Yuan Wan

Bao Gu Medicated Wine

Bao Gu Jiu

Bao Gu Zhui Feng Plaster

Bao Gu Zhui Feng Gao

Bi Yan Drops

Bi Yan Di Ji

Bi Yan Kang Tablet; Biyankang Tablet

Biyankang Pian

Biyan Tablet; Bi Yan Tablet

Biyan Pian

Bi Yan Syrup

Bi Yan Tang Jiang

🏥 Linked Health Topics

30 · diseases via target pathways

Squamous Cell Carcinoma

disease

Carpal Tunnel Syndrome

Coronary Heart Disease

Disseminated Intravascular Coagulation

Endometrial Neoplasms

📊 Meta-Analyses

3 · systematic review

CRD42022325892 Meta-analysis of ephedra appendage fine spice decoction for the treatment of all

→ Clinical research in traditional Chinese medicine

CRD42023387895 Efficacy and Safety of Ephedra for Treating Overweight & Obesity : A Systema

→ Overweight and obesity.

CRD42023403255 Ephedra-containing traditional Chinese medicine for Primary Nephrotic Syndrome i

→ Primary nephrotic syndrome (PNS) is a prevalent gl

📚 PubMed References

2 · cited research

PMID 27376063 Efficient Use of a Crude Drug/Herb Library Reveals Ephedra Herb As a Specific An

Front Cell Dev Biol

PMID 35684137 Antioxidant and Antihyperglycemic Effects of Ephedra foeminea Aqueous Extract in

Nutrients

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: ACTIVE — direct link via herb_ingredients
Ingredient ↔ Target: ACTIVE — direct link via ingredient_targets
Target ↔ Disease: ACTIVE — direct link via target_health_topics
Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables