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Ingredient
44,598
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Gene Target
15,695
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Disease
30,467
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Evidence
23,295
trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
⚗️ Ingredient
(-)epicatechin
2
Clinical Trials
0
Meta-Analyses
2
PubMed References
Top Conditions Studied with (-)epicatechin
📋 Sample Trials
NCT01856868
Use of (-)-Epicatechin in the Treatment of Becker Muscular Dystrophy (Pilot Study)
Completed · Phase 1|Phase 2
NCT03236662
(-)- Epicatechin Becker Muscular Dystrophy
Completed · Phase 2
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 33201160
Effects of (-)-epicatechin on neuroinflammation and hyperphosphorylation of tau in the hippocampus of aged mice
Food Funct · 2020
PMID 33900336
Stimulatory effects of (-)-epicatechin and its enantiomer (+)-epicatechin on mouse frontal cortex neurogenesis markers and short-term memory: proof of concept
Food Funct · 2021
⚗️ All Ingredient data fields for (-)epicatechin
⚗️ Identity
Name
(-)epicatechin
Aliases / Synonyms
(-)-Epicatechin; Epicatechin; 490-46-0; L-Epicatechin; Epicatechol; l-Acacatechin; (-)-Epicatechol; epi-Catechin; epi-Catechol; (2R,3R)-2-(3,4-Dihydroxyphenyl)chroman-3,5,7-triol
🧪 Chemistry
Molecular Weight
290.2710
LogP
1.5461
Drug-likeness
0.51
Oral Bioavailability
28.9350
H-Bond Acceptors
6
H-Bond Donors
5
Rotatable Bonds
1
🔬 Structures
Canonical SMILES
C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O
Isomeric SMILES
C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O
InChIKey
PFTAWBLQPZVEMU-UKRRQHHQSA-N
InChI
InChI=1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15-/m1/s1
🔗 External References
HERB DB
PubChem CID
CAS Number
NPASS
NPC126029
HIT
C0114
SymMap
352
TCMID
40000; 38748; 35951; 34493; 23048; 33562; 24882
TCMSP
MOL006505
TCM-ID
12161; 6946; 5847
🔍 Raw view — every non-empty column on this row (34 fields)
name
(-)epicatechin
common names
(-)-Epicatechin; Epicatechin; 490-46-0; L-Epicatechin; Epicatechol; l-Acacatechin; (-)-Epicatechol; epi-Catechin; epi-Catechol; (2R,3R)-2-(3,4-Dihydroxyphenyl)chroman-3,5,7-triol
herb ingredient id
HBIN025288
canonical smiles
C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O
isomeric smiles
C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O
inchi
InChI=1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15-/m1/s1
inchikey
PFTAWBLQPZVEMU-UKRRQHHQSA-N
mol wt
290.2710
num h acceptors
6
num h donors
5
mol logp
1.5461
num rotatable bonds
1
drug likeness
0.51
ob score
28.9350
cas id
2545/8/6; 35323-91-2
symmap mol id
352
tcmid ingredient id
40000; 38748; 35951; 34493; 23048; 33562; 24882
tcmsp ingredient id
MOL006505
tcm id ingredient id
12161; 6946; 5847
pubchem cid
72276
npass id
NPC126029
hit id
C0114
🏥 Linked Health Topics
1 · diseases via target pathways📋 Clinical Trials
2 · subject of clinical studyNCT01856868 Use of (-)-Epicatechin in the Treatment of Becker Muscular Dystrophy (Pilot Stud
→ Becker Muscular Dystrophy
NCT03236662 (-)- Epicatechin Becker Muscular Dystrophy
→ Becker Muscular Dystrophy
📚 PubMed References
2 · cited researchPMID 33201160 Effects of (-)-epicatechin on neuroinflammation and hyperphosphorylation of tau
Food Funct
PMID 33900336 Stimulatory effects of (-)-epicatechin and its enantiomer (+)-epicatechin on mou
Food Funct
How relationships are computed
- Clinical Trials / Meta-Analyses / References: direct foreign-key link via
subject_entity_id(Phase 2d wireup) - Formula ↔ Herbs: text bridge via
formulas.herbs_in_pinyinmatchingherbs.pinyin_name - Herb ↔ Ingredient:
ACTIVE — direct link via
herb_ingredients - Ingredient ↔ Target:
ACTIVE — direct link via
ingredient_targets - Target ↔ Disease:
ACTIVE — direct link via
target_health_topics - Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables