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Ingredient
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Gene Target
15,695
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Disease
30,467
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Evidence
23,295
trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
⚗️ Ingredient
Coenzyme i
2
Clinical Trials
0
Meta-Analyses
0
PubMed References
Top Conditions Studied with Coenzyme i
📋 Sample Trials
NCT02942888
The Effects of Nicotinamide Adenine Dinucleotide (NAD) on Brain Function and Cognition
Completed
NCT05849519
Small Sample，Unicentric，Randomized, Controlled Clinical Study of Coenzyme I for Injection in the Treatment of Sudden Sensorineural Hearing Loss
Unknown · Early_Phase 1
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
None linked yet.
⚗️ All Ingredient data fields for Coenzyme i
⚗️ Identity
Name
Coenzyme i
Aliases / Synonyms
nadide; 53-84-9; NAD+; beta-NAD; Codehydrogenase I; diphosphopyridine nucleotide; beta-nicotinamide adenine dinucleotide; Codehydrase I; nicotinamide adenine dinucleotide
🧪 Chemistry
Molecular Weight
663.4300
LogP
-3.6479
Drug-likeness
0.077
H-Bond Acceptors
18
H-Bond Donors
7
Rotatable Bonds
11
🔬 Structures
Canonical SMILES
C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)([O-])OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N
Isomeric SMILES
C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)(O)OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N
InChIKey
BAWFJGJZGIEFAR-NNYOXOHSSA-N
InChI
InChI=1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
🔗 External References
🔍 Raw view — every non-empty column on this row (28 fields)
name
Coenzyme i
common names
nadide; 53-84-9; NAD+; beta-NAD; Codehydrogenase I; diphosphopyridine nucleotide; beta-nicotinamide adenine dinucleotide; Codehydrase I; nicotinamide adenine dinucleotide
herb ingredient id
HBIN021229
canonical smiles
C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)([O-])OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N
isomeric smiles
C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)(O)OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N
inchi
InChI=1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
inchikey
BAWFJGJZGIEFAR-NNYOXOHSSA-N
mol wt
663.4300
num h acceptors
18
num h donors
7
mol logp
-3.6479
num rotatable bonds
11
drug likeness
0.077
tcmid ingredient id
3893
pubchem cid
5892
npass id
NPC97951
🏥 Linked Health Topics
1 · diseases via target pathways📋 Clinical Trials
2 · subject of clinical studyNCT02942888 The Effects of Nicotinamide Adenine Dinucleotide (NAD) on Brain Function and Cog
→ Mild Cognitive Impairment|NAD
NCT05849519 Small Sample，Unicentric，Randomized, Controlled Clinical Study of Coenzyme I for
→ Sudden Sensorineural Hearing Loss
How relationships are computed
- Clinical Trials / Meta-Analyses / References: direct foreign-key link via
subject_entity_id(Phase 2d wireup) - Formula ↔ Herbs: text bridge via
formulas.herbs_in_pinyinmatchingherbs.pinyin_name - Herb ↔ Ingredient:
ACTIVE — direct link via
herb_ingredients - Ingredient ↔ Target:
ACTIVE — direct link via
ingredient_targets - Target ↔ Disease:
ACTIVE — direct link via
target_health_topics - Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables