natural remedies · Ingredient
Vitamin e
Formula: C29H50O2 · MW: 430.7170000000002 · Drug-likeness: 0.359
⚗️ Identity
Name
Vitamin e
Aliases / Synonyms
alpha-Tocopherol; 59-02-9; D-alpha-Tocopherol; 5,7,8-Trimethyltocol; (+)-alpha-Tocopherol; 2074-53-5; alpha Tocopherol; Phytogermine; TOCOPHEROL
🧪 Chemistry
Molecular Weight
430.7170
LogP
8.8403
Drug-likeness
0.359
H-Bond Acceptors
2
H-Bond Donors
1
Rotatable Bonds
12
🔗 External References
HERB DB
PubChem CID
CAS Number
DrugBank
InChIKey
GVJHHUAWPYXKBD-IEOSBIPESA-N
131
Clinical Trials
110
Meta-Analyses
9
PubMed References
Top Conditions Studied with Vitamin e
📋 Sample Trials
NCT00003367
Diet and PSA Levels in Patients With Prostate Cancer
Completed · Phase 3 · Prostate Cancer
NCT03258684
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Sepsis and Septic Shock
Completed · Sepsis
NCT03333278
The Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Trial
Completed · Phase 2 · Shock, Septic|Critically Ill|Vasoplegic
NCT03872011
Vitamin C, Thiamine and Hydrocortisone for the Treatment of Septic Shock
Completed · Phase 3 · Septic Shock
NCT04160676
Therapy With Hydrocortisone, Ascorbic Acid, Thamine in Patients With Sepsis
Completed · Sepsis
NCT00169845
Beta-carotene and Alpha-tocopherol Chemoprevention of Second Primary Malignancies in Head and Neck Cancer Patients
Completed · Phase 3 · Neoplasms
📊 Sample Meta-Analyses
CRD42020170648
Effect of combined vitamin C, hydrocortisone and thiamine for patients with septic shock: a systematic review and meta-analysis
Nowadays, the mortality rate of septic shock remains as high as 50%, so the new
CRD42020203166
Hydrocortisone, ascorbic acid and thiamine for sepsis and septic shock: a meta-analysis
The effect of treatment with hydrocortisone, ascorbic acid, and thiamine for sep
CRD42020206950
Combination therapy of thiamine and vitamin C in treating patients with sepsis or septic shock: A systematic review and meta-analysis
Sepsis is a common yet complex disorder that remains one of the major causes of
CRD42020207832
Combined treatment with ascorbic acid, hydrocortisone, and thiamine for patients with sepsis and septic shock: a systematic review and meta-analysis
Sepsis rapidly progresses causing multiple organ dysfunction, and is considered
CRD42020209086
Efficacy of Vitamin C, Thiamine, Steroids for Treatment in Sepsis Patients: A Systematic Review and Meta-analysis
Sepsis or septic shock: Sepsis is an inflammatory syndrome with life-threatenin
CRD42020216665
Benefit of hydrocortisone, thiamine, and vitamin C for patients with sepsis or septic shock
Sepsis/ septic shock requiring vasopressor/ inotropic support
📚 Sample References
PMID 31607237
Vitamin E attenuates alterations in learning, memory and BDNF levels caused by perinatal ethanol exposure
Nutr Neurosci · 2021
PMID 33216086
Dietary vitamin E regulates the activity of antioxidant enzymes through Wnt10b signaling in the muscle of zebrafish
Food Funct · 2020
PMID 33617844
Vitamin E pretreated Wharton's jelly-derived mesenchymal stem cells attenuate CCl4-induced hepatocyte injury in vitro and liver fibrosis in vivo
Biochem Pharmacol · 2021
PMID 34089243
Administration of vitamin E attenuates airway inflammation through restoration of Nrf2 in a mouse model of asthma
J Cell Mol Med · 2021
PMID 34710615
Different forms of vitamin E and metabolite 13'-carboxychromanols inhibit cyclooxygenase-1 and its catalyzed thromboxane in platelets, and tocotrienols and 13'-carboxychromanols are competitive inhibitors of 5-lipoxygenase
J Nutr Biochem · 2021
PMID 35112986
Effect of α-tocopherol in alleviating the lipopolysaccharide-induced acute lung injury via inhibiting nuclear factor kappa-B signaling pathways
Bioengineered · 2022
🏥 Linked Health Topics 12 · matched via study conditions
Acidosis, Lactic
phenotype
Alzheimer'S Disease
syndrome
Amyotrophic Lateral Sclerosis
syndrome
Anemia
syndrome
Rheumatoid Arthritis
syndrome
Asthma
syndrome
Atherosclerosis
syndrome
Beriberi
syndrome
Cardiovascular Diseases
group
Primary Biliary Cirrhosis
syndrome
Delirium
disease
Diabetes Mellitus
group