natural remedies · Ingredient
Theanine
Formula: C7H14N2O3 · MW: 174.2 · Drug-likeness: 0.514
⚗️ Identity
Name
Theanine
Aliases / Synonyms
L-Theanine; 3081-61-6; N-Ethyl-L-glutamine; Theanin; Suntheanine; (S)-2-Amino-5-(ethylamino)-5-oxopentanoic acid; N5-Ethyl-L-glutamine; CCRIS 7326; C7H14N2O3
🧪 Chemistry
Molecular Weight
174.2000
LogP
-0.6854
Drug-likeness
0.514
H-Bond Acceptors
3
H-Bond Donors
3
Rotatable Bonds
5
🔗 External References
9
Clinical Trials
5
Meta-Analyses
13
PubMed References
Top Conditions Studied with Theanine
Attention Deficit Hyperactivity Disorder 2
Stress 2
Cognitive Function|Mood 1
The health-promoting properties of green tea are well establ 1
Sleep quality 1
Our systematic review will focus on human cognitive function 1
Neuropsychiatric disorders: Neuropsychiatric disorders are a 1
Schizophrenia 1
L-theanine 1
Healthy Students 1
Cortical Excitability|Psychiatric Disorder 1
📋 Sample Trials
NCT00981955
The Effects of Caffeine and L-theanine Both Alone and in Combination on Cerebral Blood Flow, Cognition and Mood
Completed · Phase 4 · Cognitive Function|Mood
NCT02770105
Theanine and Caffeine on Neurophysiology of Attention
Completed · L-theanine
NCT03533556
Effects of L-theanine and Caffeine on Attention and Attention-related Brain Activity of Children With Attention Deficit Hyperactivity Disorder
Completed · Early_Phase 1 · Attention Deficit Hyperactivity Disorder
NCT00291070
Effects of L-Theanine in Boys With ADHD
Completed · Phase 2 · Attention Deficit Hyperactivity Disorder
NCT00372151
L-Theanine in the Management of Schizophrenia
Completed · Phase 3 · Schizophrenia
NCT01361204
Anti-stress Effect of Theanine on Students During Long-term Pharmacy Practices
Completed · Healthy Students
📊 Sample Meta-Analyses
CRD42022351601
The effects of tea (Camellia sinensis) or its bioactive compounds L-theanine or L-theanine plus caffeine on cognition, sleep, and mood in apparently healthy subjects: a systematic review
Our systematic review will focus on human cognitive function, sleep, and mood.
CRD42018104792
The effects of the unique green tea amino acid L-theanine on the stress response and anxiety in human clinical trials – a systematic review of randomised controlled trials
The health-promoting properties of green tea are well established and it is cons
CRD42020191960
Theanine and cancer: A systematic review of the literature
CRD42022304635
The effects of L-Theanine consumption on sleep in humans: a systematic review
Sleep quality
CRD42023478563
Efficacy and Safety of L-Theanine in Neuropsychiatric Disorders: A Systematic Review
Neuropsychiatric disorders: Neuropsychiatric disorders are a category of medical
📚 Sample References
PMID 31837331
Theanine attenuates hippocampus damage of rat cerebral ischemia-reperfusion injury by inhibiting HO-1 expression and activating ERK1/2 pathway
Life Sci · 2020
PMID 32057039
l-Theanine regulates glucose, lipid, and protein metabolism via insulin and AMP-activated protein kinase signaling pathways
Food Funct · 2020
PMID 32402912
l-Theanine attenuates neointimal hyperplasia via suppression of vascular smooth muscle cell phenotypic modulation
J Nutr Biochem · 2020
PMID 32635404
L-Theanine Reduced the Development of Knee Osteoarthritis in Rats via Its Anti-Inflammation and Anti-Matrix Degradation Actions: In Vivo and In Vitro Study
Nutrients · 2020
PMID 33249185
L-theanine suppresses the metastasis of prostate cancer by downregulating MMP9 and Snail
J Nutr Biochem · 2021
PMID 34037653
L-Theanine regulates glutamine metabolism and immune function by binding to cannabinoid receptor 1
Food Funct · 2021
🏥 Linked Health Topics 2 · matched via study conditions