natural remedies · Ingredient
Pectolinarigenin
Formula: C17H14O6 · MW: 314.293 · Drug-likeness: 0.772
⚗️ Identity
Name
Pectolinarigenin
Aliases / Synonyms
520-12-7; Pectolinaringenin; 5,7-Dihydroxy-4',6-dimethoxyflavone; 5,7-Dihydroxy-6-methoxy-2-(4-methoxyphenyl)-4-benzopyrone; 5,7-Dihydroxy-6,4'-dimethoxyflavone; 6-methoxyacacetin; 5,7-dihydroxy-6-methoxy-2-(4-methoxyphenyl)chromen-4-one; NSC-106403; 4'-Methylcapillarisin
🧪 Chemistry
Molecular Weight
314.2930
LogP
2.8884
Drug-likeness
0.772
H-Bond Acceptors
6
H-Bond Donors
2
Rotatable Bonds
3
🔗 External References
0
Clinical Trials
0
Meta-Analyses
3
PubMed References
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 27735939
Natural product pectolinarigenin inhibits osteosarcoma growth and metastasis via SHP-1-mediated STAT3 signaling inhibition
Cell Death Dis · 2016
PMID 34500010
Neuroprotective and anti-inflammatory effect of pectolinarigenin, a flavonoid from Amazonian Aegiphila integrifolia (Jacq.), against lipopolysaccharide-induced inflammation in astrocytes via NFκB and MAPK pathways
Food Chem Toxicol · 2021
PMID 35453360
Pectolinarigenin Induces Antioxidant Enzymes through Nrf2/ARE Pathway in HepG2 Cells
Antioxidants (Basel) · 2022
🔗 Knowledge Graph Connections
Open full graph →Real research connections from HERB 2.0, TCMSP, and clinical evidence sources. 25 related entities shown — click any to follow the trail.
🌿 Herbs containing this compound · 1
🧬 Gene targets · 12
Trypsin-1
binding 0.863
Prostaglandin G/H synthase 2
binding 0.848
NCOA2
NCOA2
binding 0.815
Nitric oxide synthase, inducible
binding 0.809
Dipeptidyl peptidase IV
binding 0.803
Calmodulin
binding 0.799
NCOA1
NCOA1
binding 0.794
Sodium channel protein type 5 subunit alpha
binding 0.787
Ig gamma-1 chain C region
binding 0.780
Alpha-1B adrenergic receptor
binding 0.764
Acetylcholinesterase
binding 0.762
Prostaglandin G/H synthase 1
binding 0.759
🏥 Linked health topics · 12
Abdominal aortic aneurysm
disease
Adenomatous polyposis
disease
Alzheimer'S Disease
syndrome
Analgesics
disease
Arthritis
syndrome
Autoimmune Diseases
group
Bladder cancer
disease
Blood group, Yt system
disease
Breast cancer
disease
Cancer, unspecific
disease
Carcinoma in situ, unspecified
disease
Cardiac dysrhythmias
disease