natural remedies · Ingredient
Naringenin
Formula: C15H12O5 · MW: 272.256 · Drug-likeness: 0.742
⚗️ Identity
Name
Naringenin
Aliases / Synonyms
480-41-1; (S)-Naringenin; salipurpol; Naringenine; Salipurol; (S)-5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one; (2S)-Naringenin; pelargidanon; naringetol
🧪 Chemistry
Molecular Weight
272.2560
LogP
2.5099
Drug-likeness
0.742
H-Bond Acceptors
5
H-Bond Donors
3
Rotatable Bonds
1
🔗 External References
HERB DB
PubChem CID
CAS Number
InChIKey
FTVWIRXFELQLPI-ZDUSSCGKSA-N
0
Clinical Trials
0
Meta-Analyses
4
PubMed References
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 31758699
Naringenin attenuates non-alcoholic fatty liver disease by down-regulating the NLRP3/NF-κB pathway in mice
Br J Pharmacol · 2019
PMID 30527894
Naringenin targets on astroglial Nrf2 to support dopaminergic neurons
Pharmacol Res · 2019
PMID 21748601
Naringenin reduces lung metastasis in a breast cancer resection model
Protein Cell · 2011
PMID 21354229
Naringenin inhibits the assembly and long-term production of infectious hepatitis C virus particles through a PPAR-mediated mechanism
J Hepatol · 2011
🔗 Knowledge Graph Connections
Open full graph →Real research connections from HERB 2.0, TCMSP, and clinical evidence sources. 25 related entities shown — click any to follow the trail.
🌿 Herbs containing this compound · 1
🧬 Gene targets · 12
Prostaglandin G/H synthase 2
binding 0.880
Estrogen receptor
binding 0.876
Heat shock protein HSP 90
binding 0.836
Prostaglandin G/H synthase 1
binding 0.813
mRNA of PKA Catalytic Subunit C-alpha
binding 0.797
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, gamma isoform
binding 0.791
Beta-lactamase
binding 0.766
3-hydroxy-3-methylglutaryl-coenzyme A reductase
4-aminobutyrate aminotransferase, mitochondrial
Adiponectin
AKR1C1
AKR1C1
Apolipoprotein B-100
🏥 Linked health topics · 12