natural remedies · Ingredient
Melanin
Formula: C18H10N2O4 · MW: 318.2880000000001 · Drug-likeness: 0.332
⚗️ Identity
Name
Melanin
Aliases / Synonyms
8049-97-6; Melanin from Sepia officinalis; Melanins; 6,14-dimethyl-4,12-diazapentacyclo[8.6.1.12,5.013,17.09,18]octadeca-1(17),2,5,9(18),10,13-hexaene-7,8,15,16-tetrone; 6,14-dimethyl-4,12-diazapentacyclo[8.6.1.1^{2,5}.0^{13,17}.0^{9,18}]octadeca-1(17),2,5,9(18),10,13-hexaene-7,8,15,16-tetrone; Phaeomelanins; 6,14-dimethyl-4,12-diazapentacyclo(8.6.1.1^(2,5).0^(13,17).0^(9,18))octadeca-1(17),2,5,9(18),10,13-hexaene-7,8,15,16-tetrone; 6,14-dimethyl-4,12-diazapentacyclo(8.6.1...
🧪 Chemistry
Molecular Weight
318.2880
LogP
1.3266
Drug-likeness
0.332
Oral Bioavailability
26.4000
H-Bond Acceptors
4
H-Bond Donors
2
🔗 External References
0
Clinical Trials
2
Meta-Analyses
2
PubMed References
Top Conditions Studied with Melanin
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
CRD42020187877
Treatment of Melanin Hyperpigmentation via Lasers: A Systematic Review
Various techniques were used for gingival depigmentationtreatment. The review is
CRD42023424306
Efficacy and safety profile of antioxidants in the treatment of atopic dermatitis: A systematic review and network meta-analysis of randomized controlled trials
Atopic dermatitis (AD) a chronic inflammatory skin condition characterized by pr
📚 Sample References
PMID 32385235
Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity
Nat Commun · 2020
PMID 35180627
Orally administered melanin from Sepiapharaonis ink ameliorates depression-anxiety-like behaviors in DSS-induced colitis by mediating inflammation pathway and regulating apoptosis
Int Immunopharmacol · 2022