natural remedies · Ingredient
Isorhapontigenin
Formula: C15H14O4 · MW: 258.273 · Drug-likeness: 0.74
⚗️ Identity
Name
Isorhapontigenin
Aliases / Synonyms
32507-66-7; Isorhapotogenin; 3'-Methoxyresveratrol; 5-[(E)-2-(4-hydroxy-3-methoxyphenyl)ethenyl]benzene-1,3-diol; CZ49V3K5HS; (E)-5-(4-hydroxy-3-methoxystyryl)benzene-1,3-diol; 5-[2-(4-Hydroxy-3-methoxyphenyl)ethenyl]-1,3-benzenediol; 5-((1E)-2-(4-HYDROXY-3-METHOXYPHENYL)ETHENYL)-1,3-BENZENEDIOL; 5-[(1E)-2-(4-HYDROXY-3-METHOXYPHENYL)ETHENYL]-1,3-BENZENEDIOL
🧪 Chemistry
Molecular Weight
258.2730
LogP
2.9824
Drug-likeness
0.74
H-Bond Acceptors
4
H-Bond Donors
3
Rotatable Bonds
3
🔗 External References
0
Clinical Trials
0
Meta-Analyses
7
PubMed References
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 31817453
A Stilbenoid Isorhapontigenin as a Potential Anti-Cancer Agent against Breast Cancer through Inhibiting Sphingosine Kinases/Tubulin Stabilization
Cancers (Basel) · 2019
PMID 31222373
Isorhapontigenin (ISO) inhibits stem cell-like properties and invasion of bladder cancer cell by attenuating CD44 expression
Cell Mol Life Sci · 2020
PMID 27171279
SESN2/sestrin 2 induction-mediated autophagy and inhibitory effect of isorhapontigenin (ISO) on human bladder cancers
Autophagy · 2016
PMID 26681767
Isorhapontigenin suppresses growth of patient-derived glioblastoma spheres through regulating miR-145/SOX2/cyclin D1 axis
Neuro Oncol · 2016
PMID 33777675
Isorhapontigenin protects against doxorubicin-induced cardiotoxicity via increasing YAP1 expression
Acta Pharm Sin B · 2021
PMID 35720190
Isorhapontigenin Modulates SOX9/TOLLIP Expression to Attenuate Cell Apoptosis and Oxidative Stress in Paraquat-Induced Acute Kidney Injury
Oxid Med Cell Longev · 2022