natural remedies · Ingredient
Hyperforin
Formula: C35H52O4 · MW: 536.7970000000003 · Drug-likeness: 0.211
⚗️ Identity
Name
Hyperforin
Aliases / Synonyms
11079-53-1; hiperforina; hyperforine; CHEBI:5834; RM741E34FP; CHEMBL1237210; (1R,5S,6R,7S)-4-hydroxy-6-methyl-1,3,7-tris(3-methylbut-2-en-1-yl)-6-(4-methylpent-3-en-1-yl)-5-(2-methylpropanoyl)bicyclo[3.3.1]non-3-ene-2,9-dione; (+)-Hyperforin; (1R,5S,6R,7S)-4-hydroxy-5-isobutyryl-6-methyl-1,3,7-tris(3-methylbut-2-en-1-yl)-6-(4-methylpent-3-en-1-yl)bicyclo[3.3.1]non-3-ene-2,9-dione
🧪 Chemistry
Molecular Weight
536.7970
LogP
8.9897
Drug-likeness
0.211
Oral Bioavailability
44.0330
H-Bond Acceptors
4
H-Bond Donors
1
Rotatable Bonds
11
🔗 External References
0
Clinical Trials
0
Meta-Analyses
4
PubMed References
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 31683954
TRPC6-Mediated ERK1/2 Activation Increases Dentate Granule Cell Resistance to Status Epilepticus Via Regulating Lon Protease-1 Expression and Mitochondrial Dynamics
Cells · 2019
PMID 27881772
Store-Operated Calcium Channel Complex in Postsynaptic Spines: A New Therapeutic Target for Alzheimer's Disease Treatment
J Neurosci · 2016
PMID 20883786
Antidepressant hyperforin up-regulates VEGF in CNS tumour cells
Pharmacol Res · 2011
PMID 34025642
Hyperforin Ameliorates Imiquimod-Induced Psoriasis-Like Murine Skin Inflammation by Modulating IL-17A-Producing γδ T Cells
Front Immunol · 2021