natural remedies · Ingredient
Histamine
Formula: C5H9N3 · MW: 111.148 · Drug-likeness: 0.56
⚗️ Identity
Name
Histamine
Aliases / Synonyms
51-45-6; 2-(1H-imidazol-5-yl)ethanamine; 1H-Imidazole-4-ethanamine; Ergamine; Ergotidine; 2-(4-Imidazolyl)ethylamine; 5-Imidazoleethylamine; Eramin; Theramine
🧪 Chemistry
Molecular Weight
111.1480
LogP
-0.0891
Drug-likeness
0.56
Oral Bioavailability
44.1040
H-Bond Acceptors
2
H-Bond Donors
2
Rotatable Bonds
2
🔗 External References
3
Clinical Trials
10
Meta-Analyses
0
PubMed References
Top Conditions Studied with Histamine
Pruritus 2
Scombroid syndrome/histamine poisoning occurs worldwide and 1
Acute Myeloid Leukemia 1
Prevention of stress ulcers in pediatric intensive care unit 1
Over the last two decades antipsychotics are increasingly pr 1
Histamine-2 receptor antagonists (H2RA) are frequently presc 1
Functional dyspepsia (FD) is a common gastrointestinal disor 1
Cough, no matter the etiology. 1
Asthma 1
As the use of gastric acid suppressants such as proton pump 1
Antihistamine-refractory CSU. 1
Allergic rhinitis is a common disease characterised by nasal 1
📋 Sample Trials
NCT04399213
Dermal Blood Flow Response to Escalating Doses of Histamine, Administered by a Skin Prick
Completed · Pruritus
NCT04396977
Inter-arm and Inter-period Reproducability of the Dermal Blood Flow Response After a Histamine Skin Prick.
Completed · Pruritus
NCT01347996
Maintenance Therapy With Ceplene® (Histamine) and IL-2 on Immune Response and MRD in Acute Myeloid Leukemia
Completed · Phase 4 · Acute Myeloid Leukemia
📊 Sample Meta-Analyses
CRD42020196592
Comparative Effectiveness and Acceptability of Treatments for Antihistamine-Refractory Chronic Spontaneous Urticaria: A Network Meta-Analysis of Randomized Controlled Trials and Observational Studies
Antihistamine-refractory CSU.
CRD42012002566
Histamine food poisonings: a systematic review and meta-analysis
Scombroid syndrome/histamine poisoning occurs worldwide and it is considered one
CRD42014007115
Comparative effectiveness of intranasal steroids, leukotriene antagonists, decongestant, and second generation Histamine H1 Antagonists in allergic rhinitis of adults: systematic review and network meta-analysis
Allergic rhinitis is a common disease characterised by nasal itch, sneezing, rhi
CRD42017060887
Is histamine-2 receptor antagonists use a risk factor for infection, necrotizing enterocolitis and mortality in neonates?
Histamine-2 receptor antagonists (H2RA) are frequently prescribed off-label to n
CRD42018093606
The risk of community-acquired pneumonia in children using proton pump inhibitors or histamine-2 receptor antagonists: a systematic review<br />
As the use of gastric acid suppressants such as proton pump inhibitors (PPIs) an
CRD42019124528
Efficacy of histamine antagonist antitussive agents versus placebo in symptomatic treatment of cough: a systematic review and meta-analysis of randomized controlled trials
Cough, no matter the etiology.
📚 Sample References
None linked yet.
🏥 Linked Health Topics 1 · matched via study conditions