natural remedies · Ingredient
Glucosamine
Formula: C6H13NO5 · MW: 179.172 · Drug-likeness: 0.288
⚗️ Identity
Name
Glucosamine
Aliases / Synonyms
2-Amino-2-Deoxy-D-Glucopyranose; 2-Amino-2-Deoxy-D-Glucopyranoside; 2-Amino-2-Deoxy-D-Glucose; 2-Amino-2-Deoxy-Glucopyranose; 2-Amino-2-Deoxy-Glucopyranoside; 2-Amino-2-Deoxy-Glucose; 2-Deoxy-2-Amino-D-Glucopyranose; 2-Deoxy-2-Amino-D-Glucopyranoside; 2-Deoxy-2-Amino-D-Glucose; 2-Deoxy-2-Amino-Glucopyranose
🧪 Chemistry
Molecular Weight
179.1720
LogP
-3.2550
Drug-likeness
0.288
H-Bond Acceptors
6
H-Bond Donors
5
Rotatable Bonds
1
🔗 External References
17
Clinical Trials
13
Meta-Analyses
1
PubMed References
Top Conditions Studied with Glucosamine
Osteoarthritis 3
Osteoarthritis of the Knee 2
Knee Osteoarthritis 2
Osteoarthritis|Glucosamine|Diacerein 1
Healthy Subject 1
Risk of cancer. 1
Osteoarthritis, Knee 1
Breast Cancer|Joint Pain 1
Patients with knee osteoarthritis. Pain relief and function 1
Patients with knee osteoarthritis 1
Osteoarthritis of Knee 1
Osteoarthritis (OA), a chronic disease characterized by the 1
📋 Sample Trials
NCT00032890
Glucosamine/Chondroitin Arthritis Intervention Trial (GAIT)
Completed · Phase 3 · Osteoarthritis
NCT00086229
Absorption and Distribution of Glucosamine and Chondroitin
Completed · Osteoarthritis
NCT00377286
Effect of Glucosamine on Joint Structure and Quality of Life (JOG)
Completed · Osteoarthritis
NCT00691678
Glucosamine and Chondroitin for Aromatase Inhibitor Induced Joint Symptoms in Women With Breast Cancer
Completed · Phase 2 · Breast Cancer|Joint Pain
NCT01682694
Glucosamine and Chondroitin Effects
Completed · Inflammation
NCT03717714
Polycan in Combination With Glucosamine for Treatment of Knee Osteoarthritis
Completed · Osteoarthritis of the Knee
📊 Sample Meta-Analyses
CRD42011001295
Study sponsor, active compound, dosing, and label as explanation of inconsistency in glucosamine for osteoarthritis trials: a systematic review and meta-analysis of randomised placebo-controlled trials
Osteoarthritis (OA) is a chronic disease which can manifest itself in all synovi
CRD42016036998
Effects of glucosamine in patients with osteoarthritis of the knee: protocol for a systematic review and meta-analysis
Patients with knee osteoarthritis
CRD42017063775
Effects of glucosamine and chondroitin supplements on symptomatic temporomandibular joint disorders: a systematic review
Temporomandibular joint disorders are characterized as a group of conditions ass
CRD42018100510
The cancer risks of glucosamine containing nutritional supplements: a systematic review and meta-analysis
Risk of cancer.
CRD42020179570
Glucosamine sulphate: an umbrella review of health outcomes
GS is traditionally used for knee osteoarthritis. However this will be an umbrel
CRD42020202093
Identify the effects of the combination of glucosamine and chondroitin in patients with knee osteoarthritis: a systematic review and meta-analysis
Patients with knee osteoarthritis. Pain relief and function recovery of knee.
📚 Sample References
PMID 31204557
Glucosamine promotes hepatitis B virus replication through its dual effects in suppressing autophagic degradation and inhibiting MTORC1 signaling
Autophagy · 2020
🏥 Linked Health Topics 4 · matched via study conditions