natural remedies · Ingredient
Echinacoside
Formula: C35H46O20 · MW: 786.7330000000006 · Drug-likeness: 0.054
⚗️ Identity
Name
Echinacoside
Aliases / Synonyms
82854-37-3; [(2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate; MFCD00075695; CHEBI:4745; I04O1DT48T; DTXSID0033469; Echinacoside Ethanolate; (2R,3R,4R,5R,6R)-6-(3,4-Dihydroxyphenethoxy)-5-hydroxy-2-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)ox...
🧪 Chemistry
Molecular Weight
786.7330
LogP
-3.1917
Drug-likeness
0.054
Oral Bioavailability
3.1450
H-Bond Acceptors
20
H-Bond Donors
12
Rotatable Bonds
13
🔗 External References
0
Clinical Trials
0
Meta-Analyses
12
PubMed References
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 32014501
Echinacoside attenuates inflammatory response in a rat model of cervical spondylotic myelopathy via inhibition of excessive mitochondrial fission
Free Radic Biol Med · 2020
PMID 33330477
Echinacoside Suppresses Amyloidogenesis and Modulates F-actin Remodeling by Targeting the ER Stress Sensor PERK in a Mouse Model of Alzheimer's Disease
Front Cell Dev Biol · 2020
PMID 33378712
Echinacoside ameliorates alcohol-induced oxidative stress and hepatic steatosis by affecting SREBP1c/FASN pathway via PPARα
Food Chem Toxicol · 2021
PMID 33600859
Echinacoside improves diabetic liver injury by regulating the AMPK/SIRT1 signaling pathway in db/db mice
Life Sci · 2021
PMID 34112163
Echinacoside exerts anti-tumor activity via the miR-503-3p/TGF-β1/Smad aixs in liver cancer
Cancer Cell Int · 2021
PMID 34777682
Echinacoside Upregulates Sirt1 to Suppress Endoplasmic Reticulum Stress and Inhibit Extracellular Matrix Degradation In Vitro and Ameliorates Osteoarthritis In Vivo
Oxid Med Cell Longev · 2021