natural remedies · Ingredient
Curcumin
Formula: C21H20O6 · MW: 368.385 · Drug-likeness: 0.548
⚗️ Identity
Name
Curcumin
Aliases / Synonyms
458-37-7; Diferuloylmethane; Natural yellow 3; Kacha haldi; Indian saffron; Curcuma; Gelbwurz; Haldar; Curcumin I
🧪 Chemistry
Molecular Weight
368.3850
LogP
3.3699
Drug-likeness
0.548
H-Bond Acceptors
6
H-Bond Donors
2
Rotatable Bonds
8
🔗 External References
121
Clinical Trials
186
Meta-Analyses
199
PubMed References
Top Conditions Studied with Curcumin
📋 Sample Trials
NCT00164749
A Pilot Study of Curcumin and Ginkgo for Treating Alzheimer's Disease
Completed · Phase 1|Phase 2 · Alzheimer's Disease
NCT03066791
Turmeric and Curcumin on Sebum Production
Completed · Inflammation; Skin
NCT01831193
Effect of Oral Supplementation With Curcumin (Turmeric) in Patients With Proteinuric Chronic Kidney Disease
Completed · Phase 3 · Proteinuria
NCT03845322
Curcumin/Turmeric as a Treatment for Patients With Subdural Hematomas Recurrence
Withdrawn · Early_Phase 1 · Hematoma, Subdural, Chronic
NCT03980509
A "Window Trial" on Curcumin for Invasive Breast Cancer Primary Tumors
Active_Not_Recruiting · Phase 1 · Breast Cancer
NCT00027495
Curcumin for the Prevention of Colon Cancer
Completed · Phase 1 · Colorectal Cancer
📊 Sample Meta-Analyses
CRD42020166300
“Comparative Efficiency Of Ginger Extract Gel With And Without Curcumin Gel For Management Of Homogeneous Leukoplakia Evaluated By Salivary Malondialdehyde Level” (Biomarker)
Oral leukoplakia (OL) is the most frequent precancerous lesion of the oral cavit
CRD42022334940
Anticancer effects of gingerol, shogaol and curcumin in cervical cancer: A systemic review.
CRD42022323737
Arteannuin, fructus lycii extract and curcumin for uterine cervical carcinoma: A protocol for systematic review and meta-analysis
Cancer is a worldwide public health concern, with severe social and economic rep
CRD42019148682
Bioavailability of curcumin is a determinant of its anti-inflammatory potential in humans. A systematic review of randomised controlled trials
Inflammation is a key biological risk factor underpinning non-communicable disea
CRD42021237458
The action of curcumin against damage resulting from stroke: a systematic review
CRD42021279230
Combination of Curcumin and Photodynamic Therapy Based on the Use of Red Light or Near-Infrared Radiation in Cancer: a Systematic Review
📚 Sample References
PMID 25595578
Curcumin ameliorates high glucose-induced neural tube defects by suppressing cellular stress and apoptosis
Am J Obstet Gynecol · 2015
PMID 29807115
Curcumin suppresses oncogenicity of human colon cancer cells by covalently modifying the cysteine 67 residue of SIRT1
Cancer Lett · 2018
PMID 22258452
Targeting pioneering factor and hormone receptor cooperative pathways to suppress tumor progression
Cancer Res · 2012
PMID 21237271
Curcumin protects against A53T alpha-synuclein-induced toxicity in a PC12 inducible cell model for Parkinsonism
Pharmacol Res · 2011
PMID 26609559
Curcumin inhibits activation of TRPM2 channels in rat hepatocytes
Redox Biol · 2016
PMID 27077805
Activation of PPARγ/P53 signaling is required for curcumin to induce hepatic stellate cell senescence
Cell Death Dis · 2016
🏥 Linked Health Topics 12 · matched via study conditions
Alzheimer'S Disease
syndrome
Amyotrophic Lateral Sclerosis
syndrome
Ulcerative Colitis
syndrome
Diabetes
syndrome
Diabetic Retinopathy
syndrome
Inflammatory Bowel Diseases
group
Irritable Bowel Syndrome
syndrome
Multiple Myeloma
disease
Multiple Sclerosis
syndrome
Periodontitis
syndrome
Proteinuria
phenotype
Polycystic Kidney, Autosomal Dominant
syndrome