natural remedies · Ingredient
Bilirubin
Formula: C33H36N4O6 · MW: 584.6730000000002 · Drug-likeness: 0.215
⚗️ Identity
Name
Bilirubin
Aliases / Synonyms
635-65-4; Hematoidin; Bilirubin IX-alpha; Hemetoidin; Cholerythrin; Bilirubin IX.alpha.; 3-[2-[[3-(2-carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxopyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(Z)-(4-ethenyl-3-methyl-5-oxopyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid; MFCD00005499; Bilirubin IXalpha
🧪 Chemistry
Molecular Weight
584.6730
LogP
4.5312
Drug-likeness
0.215
H-Bond Acceptors
4
H-Bond Donors
6
Rotatable Bonds
12
🔗 External References
3
Clinical Trials
0
Meta-Analyses
7
PubMed References
Top Conditions Studied with Bilirubin
📋 Sample Trials
NCT02612207
Point-of-Care System for Determination of Bilirubin Capacity in Neonates
Completed · Jaundice, Neonatal|Hyperbilirubinemia|Bi
NCT02691156
Bilirubin Binding Capacity to Assess Bilirubin Load in Preterm Infants
Completed · Bilirubin-induced Neurologic Dysfunction
NCT05566548
Role of Bilirubin Molecular Species in Hepatic Encephalopathy and Acute-on-chronic Liver Failure
Unknown · Hepatic Encephalopathy|Acute-On-Chronic
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
PMID 32404366
Bilirubin remodels murine white adipose tissue by reshaping mitochondrial activity and the coregulator profile of peroxisome proliferator-activated receptor α
J Biol Chem · 2020
PMID 32612533
Bilirubin Protects Transplanted Islets by Targeting Ferroptosis
Front Pharmacol · 2020
PMID 32749754
Bilirubin and bile acids in osteocytes and bone tissue. Potential role in the cholestatic-induced osteoporosis
Liver Int · 2020
PMID 33746746
The Effects of Bilirubin and Lumirubin on Metabolic and Oxidative Stress Markers
Front Pharmacol · 2021
PMID 34222023
Bilirubin Restrains the Anticancer Effect of Vemurafenib on BRAF-Mutant Melanoma Cells Through ERK-MNK1 Signaling
Front Oncol · 2021
PMID 34445367
Hyperbilirubinemia Maintained by Chronic Supplementation of Unconjugated Bilirubin Improves the Clinical Course of Experimental Autoimmune Arthritis
Int J Mol Sci · 2021