natural remedies · Ingredient
Alpha-lipoic acid
Formula: C8H14O2S2 · MW: 206.3319999999999 · Drug-likeness: 0.554
⚗️ Identity
Name
Alpha-lipoic acid
Aliases / Synonyms
thioctic acid; dl-Thioctic acid; 1077-28-7; 5-(1,2-Dithiolan-3-yl)pentanoic acid; DL-alpha-Lipoic acid; 1,2-dithiolane-3-pentanoic acid; alpha Lipoic Acid; Biletan; 6,8-Thioctic acid
🧪 Chemistry
Molecular Weight
206.3320
LogP
2.7851
Drug-likeness
0.554
H-Bond Acceptors
3
H-Bond Donors
1
Rotatable Bonds
5
🔗 External References
8
Clinical Trials
38
Meta-Analyses
0
PubMed References
Top Conditions Studied with Alpha-lipoic acid
Healthy, overweight or obese individuals, and those with any 2
Women with polycystic ovary syndrome 1
Alpha-lipoic acid supplementation for type 2 diabetes patien 1
Obesity 1
Ischemic Cardiomyopathy|Diabetes Mellitus 1
Endothelial dysfunction has been considered as an early feat 1
Tolerability and efficacy of alpha-lipoic acid for the manag 1
Alpha-lipoic acid supplementation for type 1 diabetes patien 1
Burning Mouth Syndrome 1
Non-alcoholic fatty liver diseases (NAFLD) 1
Effect of riboflavin, magnesium, vitamin D, Q10, omega-3, al 1
Tinnitus in adults with chronic or acute tinnitus through th 1
📋 Sample Trials
NCT05485259
Effect of Alpha-lipoic Acid on Regression of Low-grade Squamous Intraepithelial Lesions (LSIL)
Completed · Low-Grade Squamous Intraepithelial Lesio
NCT05808946
Alpha-Lipoic Acid in Patients With Sepsis
Recruiting · Phase 2|Phase 3 · Sepsis
NCT06056687
Alpha-lipoic Acid in Diabetic Patients With Ischemic Cardiomyopathy
Completed · Ischemic Cardiomyopathy|Diabetes Mellitu
NCT06151652
Effect of Alpha-Lipoic Acid Supplementation on the Incidence of Postoperative Atrial Fibrillation in Cardiac Surgery Patients
Recruiting · Phase 4 · Postoperative Atrial Fibrillation
NCT05813496
Phase IV Trial to Evaluate Efficacy of Alpha-Lipoic Acid in Treating Symptomatic Diabetic Polyneuropathy in Egypt
Recruiting · Phase 4 · Polyneuropathy, Diabetic
NCT05729529
Impact of Alpha Lipoic Acid Efficacy in Burning Mouth Syndrome
Recruiting · Burning Mouth Syndrome
📊 Sample Meta-Analyses
CRD42016045210
Effect of alpha-lipoic acid supplementation on endothelial function: a systematic review and meta-analysis of randomized controlled trials
Endothelial dysfunction has been considered as an early feature in the progressi
CRD42017055776
Alpha-lipoic acid supplement in obesity treatment: a systematic review and meta-analysis of clinical trials
Obesity
CRD42022321714
Alpha-lipoic acid reduce CRP level: a meta-analysis of randomized clinical trials
CRP. Alpha-lipoic acid.
CRD42022322953
The effects of alpha-lipoic acid supplementation in patients with metabolic disorders related diseases: an umbrella review of meta-analyses of randomized controlled trials
However, people consume alpha-lipoic acid for these goals without having suffici
CRD42021289390
Efficacy of Alpha-Lipoic Acid for the Treatment of Carpal Tunnel Syndrome: A Systematic Review and Meta-analysis
Carpal tunnel syndrome (CTS) refers to symptoms and signs brought on by compress
CRD42021290489
Efficacy of alpha-lipoic acid (ALA) in patients with burning mouth syndrome (BMS) compared to placebo or other interventions in improving clinical outcomes.
Burning Mouth Syndrome (BMS)
📚 Sample References
None linked yet.
🏥 Linked Health Topics 2 · matched via study conditions